Prostatic inflammation is an important etiological component of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS)1. Prostate inflammation is currently detected during prostate biopsy1.
This calculator transcribes into a user-friendly digital tool the nomogramme published by Pr Gravas s, et al. Development and validation of a clinical nomogram to predict prostatic inflammation in men with lower urinary tract symptoms. Prostate Cancer Prostatic Dis. 2024 Jul 61. Please note that this tool is intended for educational purposes and not for clinical use.
Components of the PINS* nomogram1
According to the Irani score, this nomogram incorporates clinical biomarkers to estimate the likelihood of prostate inflammation:
- IPSS storage score: A component of the International Prostate Symptom Score, assessing frequency, urgency, and nocturia (OR 1.08, 95% CI 1.01–1.15; p=0.029).
- Leucocytes detected by urine dipstick: The presence of leucocytes in urine can indicate inflammation or infection (OR 6.02, 95% CI 2.10–17.24; p=0.001).
- Prostate volume over 50 mL: An enlarged prostate volume may be associated with inflammation (OR 1.92, 95% CI 1.17–3.15; p=0.009).
- Presence of diabetes mellitus: Diabetes can increase the risk of inflammation due to hyperglycemia (OR 2.07 95%CI 0.92-4.68; p=0.028).
- History of urinary tract infections: Recurrent infections can be a sign of chronic inflammation (OR 3.11, 95% CI 1.17–8.27; p=0.023).
Application and advantages of the PINS nomogram
The PINS nomogram aims to estimate a probability of prostatic inflammation based on clinical biomarkers that are familiar to urologists.
This tool/application is a nomogram, a mathematical tool that can allow clinicians, researchers, to give relative context and probabilities related to the presence of prostatic inflammation. This tool is not intended for diagnostic purpose.